Tag: ADE

Vaccine-induced immune escape

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Vaccine-induced immune escape

Vaccine-induced immune escape – COVID-19 vaccines update 68 (20 min)

New Pandemics

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New Pandemics

Not watched these yet:

Dr. Geert Vanden Bossche: Covid Mass Vaccination Triggering New Pandemics and Epidemics

 

Genetic COVID Vaccines May Damage Children’s Innate Immunity—Dr. Paul Alexander

Pandemic Restarting?!

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Pandemic Restarting?!

He warns that injecting the children is murder.  They will be made more vulnerable to  sickness and death.

Pandemic Restarting?! Geert Vanden Bossche takes a unique view (1:21)

LINK: https://streamyard.com/8ik4q75u6p7r

 

Not all anti-bodies are equal

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Not all anti-bodies are equal

Dr. Bossche’s latest prediction, mild Omicron + ADE – COVID-19 vaccines update 39 (18 min)

New theory of Dr. Bossche explains why the Omicron is surprisingly milder while becoming more infectious which leads him to also predict future outcomes of the pandemic for vaccinated and unvaccinated communities. Central to the new theory is antibody-dependent enhancement and capture of virus by sugar molecules by immune cells. Find out how the Omicron might have become such an unusual variant that rapidly took over the world due to its incredible infectivity while accidentally making the virus less dangerous for the majority of those who become infected.

Described content: Dr. Bossche theory: https://uploads-ssl.webflow.com/61600… Classical ADE and COVID: https://www.nature.com/articles/s4158… Non-classical ADE: https://www.researchsquare.com/articl… Lectins transport: https://www.nature.com/articles/s4158… Syncytia: https://www.embopress.org/doi/full/10…

Gigaohm Biological (8 March)

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Gigaohm Biological (8 March)

This is an important video which fills in a missing puzzle piece that as been known since 1998 and yet they neglect to mention it.  You hear a lot about antibodies, but this is the first time I heard about mannose-binding lectin (MBL). There are 2 main parts of the immune system: The innate or complement immune system. You are born with this. The adaptive immune system.  Antibodies belong to the adaptive system and MBS to the innate or complement system.

The lectin pathway is one of three pathways by which the complement system can be activated. This pathway is initiated by the binding of mannose-binding lectin (MBL), collectin 11 (CL-K1), and ficolins (Ficolin-1, Ficolin-2, and Ficolin-3) to microbial surface oligosaccharides and acetylated residues, respectively. MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system.

Tiny Bombs in your Blood – The Complement System (8 min)

Immunity is more than the presence or absence of antibodies

Opsonization is the process of recognizing and targeting invading particles for phagocytosis. Opsonins are extracellular proteins that, when bound to substances or cells, induce phagocytes to phagocytose the substances or cells with the opsonins bound. Thus, opsonins act as tags to label things in the body that should be phagocytosed (i.e. eaten) by phagocytes (cells that specialise in phagocytosis, i.e. cellular eating). Different types of things (“targets”) can be tagged by opsonins for phagocytosis, including: pathogens (such as bacteria), cancer cells, aged cells, dead or dying cells (such as apoptotic cells), excess synapses, or protein aggregates (such as amyloid plaques). Opsonins help clear pathogens, as well as dead, dying and diseased cells.

Here follows a simplified version of what Jonathan is saying using the articles below. Sars_CoV-2 can bind MBL. Mannose-binding lectin (MBL) are long floppy sticky chains or oligomers (like polymers but shorter).  These chains do not recognize epitopes, but they identify glycosylation patterns  -repeating carbohydrate patterns making things stick together so that macrophages can clean them up so that the complement system can be called in to for them to be degraded.

Patients who were genetically deficient in Mannan Binding Lectin (MBL) became resistant to infection when MBL was transferred from healthy people. If you have susceptibility to HIV it could be because defective MBL protein they know it opsonizes influenza…and it binds to gp120 HIV so it will bind the spike protein which has gp120 HIV. So the spike protein is attracting lectin. Lectin is one of the main ways that macrophages are being activated. Dysregulated macrophages and neutrophils overload -overstimulation of lectin may be causing ADE where the antibodies block IgM and the complement system?

MBLs and Immunity–Gigaohm Biological High Resistance Low Noise Information Brief: Biology Served Fresh Daily

Starts at 4:45min 1:12min long.  The MBL section starts at approx. 50 min

Min                                          Article
50 Mannose-binding lectin in innate immunity: past, present and future
56 Enhanced Antiviral and Opsonic Activity of a Human Mannose Binding Lectin and Surfactant Protein D Chimera
57 Reconstitution of Opsonizing Activity by Infusion of Mannan-Binding Lection (MBL) to MBL-Deficient Humans
58 Impact of Mannose-Binding Lectin on Susceptibility of Infectious diseases Binds to gp120HIV
59 Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection
1:04 Anti–spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection

 

Stop Condons

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Stop Condons

It is becoming clear that enormous risks have been taken with this experimental procedure which is the precursor platform to gene therapy.  The Fourth Industrial Revolution is riding on this new technology and they have pushed ahead despite all the unknowns. In order to make it work they had to stabilize the mRNA otherwise it would be degraded by the body. They did this by methylating the uridine to pseudouridine.

However, this can cause other problems such as reading through “stop condons”.  If you have no idea what I am talking about I suggest you look at this previous article and specifically watch the video at the end with Dr Kevin McKernan and Dr. Jay Couey.

Sherlock Ohmes

 

A cell replicates itself using its genomic intels. To do this, it reproduces what is available in DNA, until the stop codon (red) is met. The orange area is the most important part to get a perfect clone that does exactly what it is intended to do but, there is a way for the 3′-UTR (purple) to be included in the duplicated cell, which produces a cell that does something else. Something unknown.

3′-UTR is the Three prime untranslated region . In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally influence gene expression.

Putting on the brakes

In order to prevent this happening they have put more than one stop condon in.

Why use two stop UGA codons instead of one in the spike protein mRNA for the BioNTech/Pfizer SARS-CoV-2 vaccine?

 

Read Through

People have valid concerns that “read through ” will occur on the stop condons and it is known that in certain circumstances antibiotics can cause this. Here are some comments discussing the problem.

RefSeq curation and annotation of stop codon recoding in vertebrates

So it’s the alteration from uridine to pseudouridine allowing the codons to be read in the ribosome to instruct it to make the artificial S protein, but in the very act of that alteration, it screws up the “genetic compiler”, thereby misreading the code and translating the 3’UTR? There is a good chance that at least some (how many?) will readthrough causing the 3_UTR to be translated and attached to Spike Protein. And then that could cause Spike to mis-fold somehow (on this see McKernan). But NO testing was ever done to see what happens. They didn’t want to know.

If they already had their perfect 5’UTR in 2019 they wouldn’t have had to test 280,000 new ones, but what do I know eh?

OAS and ADE

Original Antigenic Sin and Antibody Dependent Enhancement.

 

The “original antigenic sin” and its relevance for SARS-CoV-2 (COVID-19) vaccination

Conclusion

What would I know?   I am not a geneticist just a bucket chemist. However, I know enough to hear alarm bells sounding. Especially when pharma hides data.  Especially when they have indemnity.

Biohazard Alarm[WARNING: The sound is very LOUD] 49secs

Omicron puzzle

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Omicron puzzle

We are hearing that Omicron is de-attenuating and that although it is far more infectious (like chicken pox) it is less pathogenic (much milder). In other words it causes less deaths and hospitalizations.  That can only be a good thing and reason for optimism. It could be that the current Omicron scare is just a propaganda fear ploy to get us all vaccinated.

However, I can also find information that this may just be a sort of intermediary phase before a boost in pathogenicity.  I keep thinking of Marek disease.  Omicron is already an escape variant that avoids the vaccine. It can spread to  the vaccinated and the unvaccinated.  What if it reverts back to type under the pressure of constant vaccinations? What if selection pressure makes it more pathogenic and more transmissible?   I truly believe this will go all the way until the last variant for which they have reserved the letter Omega (the end or last). What if they want us all enslaved to the corporate needle giving them the power of life and death?   This is what happens with Marek disease. Only vaccinated chickens live and the unvaccinated (sentinel) chickens died. They destroyed healthy chickens and healthy chicken immune systems.  Do you want to be dependent on a corporate needle for your life?   Do you want to give them the power of life and death?    The only way to stop this is to stop the vaccinations and burn the bio-labs down to the ground.  I am praying that the latest solar flares will do the job.    They are men not gods and they will die like men.

A voice of witnessing is raised up against you: Repent

 

This Comment from Mainpain (Raccoon bunker Discord)

1. My prediction is that the waxxinated will get much more infected than the unwaxcinaated and thus will also end up more in the hospitals as the unwaxcinated. So why is that? We now know that the virus is able to infect and replicate in CD4+ T cells and since the body of the waxcinated are constantly producing these CD4+ T cells when the virus enters the body it will find plenty of CD4+ T cells to infect and replicate itself in. Unwaxcinated don't have that problem since the natural immune system nicely regulates these CD4+ T cells and only produces them when they are needed. Soon this pandemic will become the pandemic of the waxcinated which is exactly the opposite of the propaganda as usual. Nothing new here.

2. Fauci said in 1984 NIH aids lecture, that if he wanted to cause maximum damage to the immune system, as an immunologist he'd pick the CD4 T cell. Indeed from thailandmedical news: The team was able to detect SARS-CoV-2 RNA in primary CD4+ T cells but not CD8+ T cells. The team also detected different SARS-CoV-2 RNAs in infected CD4+ T cells. Notably, the viral RNA level increases with time and they identified the presence of the negative strand (antisense) of SARS-CoV-2 in the infected cell, demonstrating that the virus is able to assemble viral factories and replicate in T helper cells. Plaque assay also revealed that SARS-CoV-2-infected CD4+ T cells produce infectious viral particles. COVID-19 Study Reveals That SARS-CoV-2 Uses CD4 Cells To Infect T-helper Lymphocytes. COVID-19 A Potent Version Of Airborne HIV? Sep 30, 2020 https://www.thailandmedical.news/news/breaking-news-covid-19-study-reveals-that-sars-cov-2-uses-cd4-cells-to-infect-t-helper-lymphocytes--covid-19-a-potent-version-of-airborne-hiv SARS-CoV-2 Uses CD4 to Infect T Helper Lymphocytes Sep 28, 2020 https://www.medrxiv.org/content/10.1101/2020.09.25.20200329v1 SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia Sep 14, 2020. https://www.biorxiv.org/content/10.1101/2020.07.17.209288v3 "Once inside T helper cells, SARS-CoV-2 assembles viral factories, impairs cell function and may cause cell death." Similar to HIV and CD4 cells. (edited)

 

Dan thinks it will re-attenuate

If that happens we have the worst of both worlds….more transmissible and more deadly.

Conclusion

We have to wait to see how this plays out and gather more data.  Personally speaking I refuse to give into fear.  Have faith…in the long run the survival rate of everyone drops to zero.  What we need to do is STOP VACCINATING NOW and let it play out.  God does not intend for mankind to become extinct…but he will punish the wicked. What we need now is a big solar flare and some earthquakes to destroy these factories and infrastructure.  That should slow them down.  From my mouth to God’s ear.