Natural change
No matter what man does he cannot stop natural change. How foolish is humanity to think they can stop the power that animates the universe. It is the height of arrogance. In the end we do not control anything. Not the time of our birth nor the time of our exit. Nor do we control the times or the seasons and they are a changing.
"That thou givest them they gather: thou openest thine hand, they are filled with good. Thou hidest thy face, they are troubled: thou takest away their breath, they die, and return to their dust" (Psalm 104:28-29).