Tag: PEG

State of Grace

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State of Grace

Highly recommended

Listening to this now. Christie Laurie Grace is impressive and on top of her brief.  Highly recommend.  Excellent interview.  I pointed out more than a year ago that LNP was a problem (one of many problems)…but what would I know…I am just a bucket chemist.  In fact if you do a search on this website you will find articles where I mention the dangers of LNPs especially PEG.

Lipid Nanoparticle Toxicity – Christie Laurie Grace (3:58)

I immediately subscribed to her twitter and sub- stack. This is her twitter:

https://twitter.com/_HeartofGrace_

She mentioned a webinar by Precision Nano Systems and they have a YT channel worth checking out.

https://www.youtube.com/@PrecisionNanoSystems/videos

Experiments

They are using us like lab monkeys and trying all sorts of new things out.   They knew that there would be terrible side effects and death but that did not stop them

Lipid Nano Particles (LNP)

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Lipid Nano Particles (LNP)

Not watched this yet but as an industrial Chemist substances like the LNP substance PEG (Poly ethylene glycol) were used as surfactants/stabilisers in polymer shoots.  Something that was put in a chemical reactor not something injected into the blood stream.  When I first heard it I was flabbergasted.

 

Lipid Nanoparticle (LNP) Harm

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Lipid Nanoparticle (LNP) Harm

Told you so….

 

Here is the video in the tweet:

RTE Discussions #8 (Take Two): Evidence of Lipid Nanoparticle Harm With Marc Girardot (1:29)

 

Millions unaffected by vaccines

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Millions unaffected by vaccines

This is the main argument you hear from people.  Some have had three vaccines (or more) and they are OK.  Millions of doses have been distributed and millions of vaccinated people are fine.  So what is the fuss?

This is a multi-faceted problem.  Firstly, we are all genetically different and some people can smoke and drink and abuse their bodies all their lives and live to a ripe old age. So there is a spectrum. Some people will have an immediate allergic reaction but in other people the constant doses every three months will gradually destroy the immune system.  It is not for nothing that we see huge increases in excess mortality for cardio-vascular and neurotropic diseases as well as cancers.  We now know that it is dose dependent…the more jabs the greater chance of a bad outcome.  Common sense.  You are playing Russian Roulette.  Will it be the next shot that tips your system into accelerated senescence?  Go on…just one more shot….just do it….just do it….you know its not in the chamber (lolz).  Pharma is betting on you doing it.  Please don’t deprive them of making a killing.

Degraded mRNA

We know the mRNA needs to be kept cold otherwise it degrades.  Originally they said -72°C  but that is not practicable even for hospitals (it would mean storage in liquid nitrogen). Heat and UV light will break down the mRNA and it will not  be effective.    This is why so many people still catch covid.  The body will get all sorts of degraded proteins and hopefully it will deal with the junk mRNA and clean up the mess.   So your vaccine was not effective but at least it did not make you sick.  However, if you get a purer form (lets say 80% mRNA) then you will start getting more side effects from the vaccine spike.  Northern blot has been performed on the vaccine and all sorts of protein fractions can be discerned so it is not “pure” mRNA but mRNA with junk.

Stabilized mRNA

As we pointed out in other articles they have attempted to stabilize the mRNA by methylating the uridine to pseudouridine.  This means that the body will not break down the mRNA before it can do  its job but that comes with other problems such that the RNA can possibly read through stop condons (run the red light) and encode mutant proteins forming G-quadruplexes.  When you run a red light you can cause a crash (sometimes).

Quality concerns

Not only can the mRNA be degraded  but we know that the vaccines are contaminated. Different people (including Dr Kevin McCairn) have tested them and found metals and other contaminants that come from the production process.  I used to run a lab as a Senior Chemist so I know how difficult it is to scale something up from micro-grams in a clean-lab environment using “glassware” to a major manufacturing plant (often in the third world).  What quality guarantees do we have?   We have none because it does not matter as they are not liable.   Why did our government agencies not independently test the vaccines for contamination (particulates etc)?    Back in the day I would not be allowed to send out a batch of polymer for water treatment unless it was tested and adhered to the specifications.  We even kept samples of old batches in an archive  so that we could retest them in case we got a complaint.  That was a product for waste water treatment not something injected into the blood stream.

Injecting

Which brings me to injecting and injection techniques which makes a big difference. An intramuscular injection is designed to deposit medications deep into muscle tissue and is used to prevent medication leakage, particularly for oily injections (PEG). Displace the skin and subcutaneous tissue by pulling the skin….

The trouble is that the vaccine does not stay in the muscle as pharmacokinetic studies show distribution throughout the body into all organs and persistence in the lymph system for at least sixty days.  And then there is the PEG (Poly Ethylene Glycol) which is used as an LNP (Lipid Nano Particle) like a little “fat (lipid) bubble” to “package the mRNA for delivery.  I have used PEG as a surfactant in huge reactors when shooting co-polymers but I would never put it in my blood stream.  PEG is a long chain polymer  the characteristics of which are determined in part by the length.  Once again (Knowing how polymers work) what chance is there of getting the exact molecular faction that you want?  And how pure is the PEG?   Who is doing the quality control?  Is it being made in a third world country? PEG can cause Antiphospholipid  syndrome which is a condition in which the immune system mistakenly creates antibodies that attack tissues in the body and causes clots.

Placebo

Dr Kevin McCairn has tested the vaccines live on camera and some of them contain no Phosphorus.  That means that no mRNA is present.  It seems like they deliberately left some batches as placebos.

Conclusion

If someone tells you they had three vaccines and are OK then they are very lucky.   They either got degraded batches or placebo batches…..or it could be that they will go into accelerated senescence in the next few years.

 

Gigaohm Biological (July 28)

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Gigaohm Biological (July 28)

Phoshpholipid

Another excellent presentation with Walter Chestnut discussing his latest findings, also commenting on a Robert Malone video who warns about the LNP delivery mechanism causing problems such as PEG micelles stimulating production of anti-PEG IgM, which led to accelerated clearance of subsequently administered PEGylated liposomes. According to A review on phospholipids and their main applications in drug delivery systems, Phoshpholipid–PE–PEG mixtures could form micelles rather than liposomes if PE–PEG content exceeds certain critical limit.  Of course the PEG  interests me because it is used along with surfactants for micelle formation in polymerisations.  I never thought something like that would be injected into people (lolz). Below is actually a good resource on Lipids (have a look at all the pages very informative):

 

Heavy metals play a role in neurodegeneration  but lipids are important as  Anticardiolipin and other antiphospholipid antibodies (are found) in critically ill COVID-19 positive and negative patients Antiphospholipid antibodies (APLAs) are biomarkers of a spectrum of clinical features observed in antiphospholipid syndrome (APS).1 Features of APS include venous and arterial thrombosis involving multiple organs and having various presentations. Positive APLA serology was associated with more severe disease regardless of COVID-19 status.  Moreover, Persistent lgG anticardiolipin autoantibodies are associated with post-COVID syndrome.  Persistence of various symptoms in patients who have recovered from coronavirus disease 2019 (COVID-1 9) was recently defined as ‘long COVID’ or ‘post-COVID syndrome’ (PCS). They conclude that Immunoglobulin G (lgG) anticardiolipin autoantibodies (aCL) are associated with the severity of COVID-19.  In other words an allergic or inflammatory reaction to lipid (in the heart) but also “…persistence of the virus, especially in the nervous system, could be suggested with a post-infectious inflammatory or autoimmune reaction”.  Might this have something to do with pumping the body full of phoshpholipids and mRNA spikes? What do I know? (I am just a bucket chemist who used to mix this stuff in buckets not in human bodies).

Unfortunately, many of Walter’s hypothesis are proving to be correct. He is an avid reader of the medical literature and a talented dot-connecter with a big picture overview. His sub-stack is highly recommended.  In his latest article he shows how amyloid is a double-edged sword. A large build-up will cause problems, but amyloids also serve protective functions – against autoimmune attacks.  So, they are symptomatic rather than causal factors.

Comment: Repeated infection with covids is not good even for the unjabbed and even if they got over it before. A least the omicrons have the PrP silenced. But the HIV and the other nasties and all the humanized nucleic acid etc tacked into the spike yes, will be immune insults that will catch up with us the older we are. Shortened lifetimes, yes. The younger the less shortened. Of course, the jabbed are the ones who will suffer shortest lives.

More study is needed into the mutagenic properties of the spike-protein. Perhaps this explains Nucleic Acid Acid Based Therapeutics against Respiratory Infections?

Comment: The prion promoting sequence in the spike also promotes amyloidosis. They are seeing where there won't be a positive D-dimer test but when they put blood under the scope then you see the amyloid building up. The amyloid is causing the clotting, the heart damage, etc. They look for a test for amyloid in those "rare" pre-jab liver inflammation cases and they find amyloid build up and light chains. The hepatitis victims go on to be found Dx with myloid leukemia (if I have the name correct). The Chinese are making more targeted covid viruses - but it is US research over 25 years that developed those - there is research trail from Baric, Daszak and others and a lot of patents. Baric collaborated with Shi - he trained her! That enrichment is bad news - they did that in the jab for a lot of reasons - it throws off all kinds of cascades along with the defanging IFN-1. IFN-1 has all these cascades which include regulatory ones to down regulate inflammation. But that is all gone because of the jab made to evade being recognized and take IFN-1 out. Enriching with C-G over-glycosylates it possibly more than HIV is so it sails on by more so than the virus construct.

This is very complex and there is so much that we do not know. As someone commented.

Code that codes for multiple things depending happening on how it’s parsed with the folds everybody producing the spikes internally become a mini gain of function study. multiply by a billion consecutive studies running concurrently.

It is not just the structure of the protein but how it folds and polarity as in hydrophilic or hydrophobic nature and charge.  Who is to say that the same protein might not fold differently under other circumstances thereby acquiring different properties?  Repeat expansions have been proposed to cause disease by both the repeat RNA forming foci that sequester RNA-binding proteins and through toxic dipeptide repeat proteins generated by repeat-associated non-ATG translation discussed in the article  G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.  

C9orf72 (chromosome 9 open reading frame 72) is a protein which in humans is encoded by the gene C9orf72. The protein is found in many regions of the brain, in the cytoplasm of neurons as well as in presynaptic terminals. The mutations in C9orf72 are significant because it is the first pathogenic mechanism identified to be a genetic link between familial frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). The mutation of C9ORF72 is a hexanucleotide repeat expansion of the six-letter string of nucleotides GGGGCC.

I wonder, I wonder if pumping the body full of mRNA instructions to make spike proteins will deliver the spike proteins that they want?  We know already that the mRNA vaccines are not pure but contain fragments.   The start codon of a gene is always “ATG” so repeat associated non-ATG translation means that it does not read the correct starting point, or you could say that it reads through the stop condon (runs the red light).  It looks like read-through can cause disease. Is that why the above experiment attempted to improve dementia using small peptides that stick to the G-quadruplex?

Walter Chesnut LIVE: Gigaohm Biological High Resistance Low Noise Information Brief (2:50)

Dr. Richard Fleming interview

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Dr. Richard Fleming interview

update 1.1

Dr Richard Fleming interviewed by Dr Kevin McCairn.   Of particular interest to me was the mention that PEG may play a role in the injuries that we are seeing.   Dr Ryan Cole who is a pathologist has been finding long rubbery clots in peoples veins during autopsies.

I am hoping that Kevin can get hold of some material and have a look at it.   I came across this article PEG–Peptide Conjugates by Ian W. Hamley where it says this under section 7:

7 PEG Crystallization Effects on Self-Assembly
For PEG of sufficiently high molar mass, crystallization is observed in the dry state. This can influence the nanostructure observed for PEG–peptide conjugates, for example, by TEM, where the specimen is dried. We have found that PEG crystallization can overwhelm peptide fibrillization if the latter is not strong. This was investigated for a series of PEG–peptide conjugates: FFKLVFF–PEG3k, AAKLVFF–PEG3k, and KLVFF–PEG3k. Fibrillization, as characterized in particular by the presence of a cross-β amyloid structure as well as by the macroscopic morphology, was disrupted for the conjugate containing the weak fibrillizer KLVFF, whereas fibrils were retained (on drying) for the conjugates containing the stronger fibrillizers AAKLVFF and FFKLVFF containing additional hydrophobic AA or FF units.

The clot looks like some kind of fibrin but is very unusual.Maybe some kind of polymerization?  The article also talks bout how PEG can be used to make hydrogel which interested DAPRA.  Carrie Madej used to go on about hydrogel nanotechnology in the same way that Kaufman banged on about exosomes.  They are both con-artists but perhaps they were running “spoiler” operations to make anyone mentioning these topics look crazy.  We know know that EV’s and exosomes can act like pseudo-viruses  and uptake the s-protein so perhaps the grifters were used to muddy the waters?  In any case PEG is interesting and the chemistry is advanced (I am only a bucket chemist). It is even used in Blood Substitutes to oxygenate blood.

Dr. Richard Fleming – Conflicts of Interest of Dr’s Robert Malone & Peter McCullough (1:44)

Very interesting information on Conflicts Of Interest.   

Dojo Time-Stamps

 

mRNA stability

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mRNA stability

This post was inspired by the Couey vs Wilson debate which I am still transcribing and which can be found here:

Couey vs Wilson debate

The debate got rather heated and complex on the question of whether or not mRNA is an adjuvant or a self-adjuvant as their are studies that indicate that it could be used as an adjuvant.  Now, an adjuvant is a compound or chemical that irritates or triggers the immune system.

All vaccines have adjuvants and Dr Wilson (citing a scientific study) showed that mRNA could act as a self-adjuvant.    In other words there would be no need for the addition of an adjuvant.    The objection voiced by Jonathan was that mRNA is highly immunogenic. In other words it could trigger all sorts of autoimmune diseases and inflamation, especially if it was free floating in the blood.

In order to prevent this they need to do two things 1. encapsulate the mRNA in a Lipid Nano Particle (LNP)  and 2. stabilize the mRNA.  It turns out they do use PEG and polysorbate 80 as adjuvants.

 

PEG is a long chain polymer and its characteristics are different depending on the length of the polymer chain.  Polysorbate 80 is similar to PEG.   I have useed these substances as surfactants etc when making polymers. They have certain hydrophobic and hydrophilic qualities which can be used when mixing aqueous and oil phases and in micelle formation. The above paper lists MF59 adjuvant as an emulsion adjuvant composed of an oil phase (squalene 4.3%): and an aqueous phase (polysorbate 80:0.5%, sorbitan trioleate 0.5%). These vaccines do use an adjuvant, therefore Dr Wilson was incorrect.

Polyethylene glycol

A PEGylated lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2. Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids. Proprietary lipid technology is used for each. In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol.[medical citation needed] As of December 2020 there is some concern that PEG could trigger allergic reaction, and in fact allergic reactions are the driver for both the United Kingdom and Canadian regulators to issue an advisory, noting that: two “individuals in the U.K… were treated and have recovered” from anaphylactic shock. As of 18 December, the US CDC stated that in their jurisdiction six cases of “severe allergic reaction” had been recorded from more than 250,000 vaccinations, and of those six only one person had a “history of vaccination reactions”

Two things to mention here, firstly, many of the anaphylactic reactions are cause by the adjuvants like PEG and secondly, PEG and other polymers are being examined as delivery mechanisms for drugs because they cross the Blood Brain Barrier (BBB). If that is the case then they should also be able to deliver the spike protein across the BBB and evidence is emerging that happens.  That is not a good thing. There is a reason the brain is protected and segregated from the circulatory system and while it might be desirable to cross the BBB to treat diseases like dementia and Parkinson’s it comes with a risk.

So, as far as the debate is concerned Jonathan is correct. The vaccines do have an adjuvant and it is a LNP.  Note that the Wikipedia quote above uses the word excipient rather than adjuvant. An excipient is an inactive substance ….but is it really inactive? How can it be “inactive” when PEG antibodies are found and when some people suffer anaphylactic shock?

Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

Pseudouridine

Wilson claimed that the self-adjuvant effect of mRNA was due to the pseudourodilatation of the mRNA. Pseudouridine is supposed to be more stable.

Ψ (pseudouridine) is also found in mRNAs which are the template for protein synthesis. Ψ residues in mRNA can affect the coding specificity of stop codons UAA, UGA, and UAG. In these stop codons both a U→Ψ modification and a U→C mutation both promote nonsense suppression.[6] In the SARS-CoV2 vaccine from BioNTech/Pfizer, also known as BNT162b2, Tozinameran or Comirnaty, all U's have been substituted with N1-methylpseudouridine,[7] a nucleoside related to Ψ that contains a methyl group added to N1 atom.

This is the tweet (second one Tishbite) that I sent out (well worth reading):

 

They’ve fiddled around with codon optimization to increase stability, but that translates into (1) enormous quantities produced of spike and (2) a different spike protein which could be even more pathogenic.

 

In case the above tweet disappears the link takes you here:

https://berthub.eu/articles/posts/reverse-engineering-source-code-of-the-biontech-pfizer-vaccine/

They are making people disappear off twitter (and FB)….this guy is good:

Conclusion

None of that fills me with confidence especially the fact that it can misfold.  That can lead to prions and neurodegeneration. Expect to see more diseases of the Central Nervous System,  dementia, Parkinson and CJD as well as more strokes, cancers and heart attacks. Don’t let them go anywhere near the kids with this.  We have been warning for more than a year and a half.  Is anyone listening?