Gigaohm Biological and Kevin McKernan (July 20)

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Gigaohm Biological and Kevin McKernan (July 20)

Kevin McKernan  the microbiologist and geneticist is interviewed by Dr Johnathan Couey. Kevin McKernan  worked on the human genome project and invented revolutionary sequencing technologies that dropped the cost of sequencing a human genome from $300M to $3,000; a 100,000-fold improvement in sequencing speed and cost in a few years. The following article (below) is mentioned in the Gigaohm video and explains how Twitter is trying to censor legitimate scientific debate.

Kevin McKernan makes interesting observations about the patent (conversion of uracil to pseudouridine). If something is “natural” it cannot be patented. They are lying when they say it is “natural” and the reason they do is because the royalty stream is worth between 5-10 billion dollars.

This video is difficult to follow unless you are a microbiologist or geneticist but basically (very simply put) the mRNA strand code is placed inside a Lipid Nano Particle (LNP). They use polymers like PEG (Poly Ethylene Glycol) to form a “charged fatty bubble” with the mRNA inside. The mRNA has been “stabilized” and/or “optimized” (the uracil has been methylated to Ψ) so that enzymes do not cut it up. The LNP merges with the cell and the mRNA delivers the instructions to your cell to make spike-proteins. However, questions remain whether the methylated mRNA can read through stop condons (run the red light). Moreover, we are informed that the mRNA codes for spike protein but does it create other fragments? The blotting test suggests it does. If the mRNA is not pure what sort of products are you actually expressing? This is a recipe for transcription errors and misfolding which leads to amyloidosis and prion disease.

Short Glossary

Ψ is also found in mRNAs which are the template for protein synthesis. Ψ residues in mRNA can affect the coding specificity of stop codons UAA, UGA, and UAG. In these stop codons both a U→Ψ modification and a U→C mutation both promote nonsense suppression.[8] In the SARS-CoV2 vaccine from BioNTech/Pfizer, also known as BNT162b2, Tozinameran or Comirnaty, all U’s have been substituted with N1-methylpseudouridine,[9] a nucleoside related to Ψ that contains a methyl group added to N1 atom.

Stop condon
A stop codon is a sequence of three nucleotides (a trinucleotide) in DNA or messenger RNA (mRNA) that signals a halt to protein synthesis in the cell. There are 64 different trinucleotide codons: 61 specify amino acids and 3 are stop codons (i.e., UAA, UAG and UGA).

Read through
Stop-codon read-through refers to the phenomenon that a ribosome goes past the stop codon and continues translating into the otherwise untranslated region (UTR) of a transcript.

Transcription errors
Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of DNA polymerase and errors are amplified >1000-fold due to translation.

Northern Blotting
Northern blot is a laboratory analysis method used to study RNA. Specifically, purified RNA fragments from a biological sample (such as blood or tissue) are separated by using an electric current to move them through a sieve-like gel or matrix, which allows smaller fragments to move faster than larger fragments (western blotting is used for proteins).

Northern Blot Method – Animation video (8 min)

Kevin McKernan Revisited: Gigaohm Biological High Resistance Low Noise Information Brief (1:20)