Category: Kevin

Double Dose

Posted on

Double Dose

A double dose of Dr McCairn discussing the neurological implications of both Covid and of the vaccine.  The videos come with a warning to anyone triggered by racism as the particular target is Ian Copeland a supposed PhD but in actual fact a CRT pharma tool with his side-kick Drew who both boast about “black excellence” and use racism to shut down any debate. The problem is that these douche bags are still pushing the vaccine onto their communities. They will not (and cannot) discuss the science and therefore a meme war was launched (lolz).  Nothing is untouchable especially when you are being paid to poison people all the while playing the victim. Sounds a bit like the antisemitic playbook and the cultural Marxist game-plan.

The top video discusses Vaccine Immunometabolism in the brain and this was the takeaway line for me:

"The observed alterations in biochemical profiles upon incubation with COVID-19 mRNA in the specific organelles of the glial cells are similar to those we observe for brain cancer vs grade of aggressiveness".

The other (second) video looks at the neurological protein signature of the virus itself this was the take away for me on this paper:

This video also discusses the increasing excess deaths in the Office of National Statistics in the UK (at about 42 minutes I believe) followed by a segment highlighting the Australian Parliament rejecting any investigation into excess deaths. The overall conclusion is that both the virus and the vaccine have neurological implications.

 

Decoding COVID19 mRNA Vaccine CNS Immunometabolism (2:07)

Oz Covering Up Excess Deaths, Proteomics of SARS (Neurodegeneration – Implications For Vaccines)-1:55

Discussing PRIONS

Posted on

Discussing PRIONS

A very good discussion and I have added some important topics under the video.

Discussing PRIONS (SARS & Gene-Transfection) With Walter Chestnut

Covering their tracks

When they do an autopsy if they find Spike Protein without nucleocapsid protein they know that it came from the vaccine. If they find nucleocapsid alongside spike they know it came from the virus. If future mRNA “vaccines” encode for nucleocapsid as well as Spike Protein they will no longer be able to determine whether the death was cause by the “vaccine”.

This new development will potentially obscure or mask the difference between these antigens in SARS-2 versus injection context. With mRNA encoding nucleocapsid, the vaccine injury and death can be falsely attributed to covid19 infection.

Complexity

What did Clint Eastwood say as he dispatched a bad guy?    Something like, “a man has to know his limitations”.   We are messing with things that we barely understand.  The complexity is astounding and we think we know it all.  The hubris is breathtaking as the geneticist Kevin McKernan (who recently discovered plasmid DNA with SV40 promoters in the vaccines) points out:

All cause mortality keeps going up

The Molecular Bomb

Posted on

The Molecular Bomb

Highly recommended stream. Dr Kevin McCairn talks with @DoorlessCarp (Dave) [https://doorlesscarp953.substack.com/ ] and Genervter Burger (Annoyed Citizen) [https://genervter.substack.com/p/der-weg-richtung-himmel-oder-holle  Any missing links can be found on the substack]

The Molecular Bomb: Why Nuking miRNA Signaling With Synthetic mRNA Is A bad Idea (3:00)

 

So RNA is usually protected from being broken down because it is inside exosomes or protected by lipids (fatty compounds) but now we discover RNA on the surface of cells

19 min Extracellular RNAs: A New Awareness of Old Perspectives
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509047/

24 min Human genome-produced RNA discovered on surface of cells.
https://www.drugtargetreview.com/news/70823/human-genome-produced-rna-discovered-on-surface-of-cells/

30 min The impact of BNT162b2 mRNA vaccine on adaptive and innate immune responses https://www.medrxiv.org/content/10.1101/2021.05.03.21256520v2
The vaccine stopped working after six months and changed the immune cells sequences as well as the built -in (inate) interferon immune response (higher IL-1/IL-6 release and decreased production of IFN-α.)

Down-regulating innate AND adaptive immune response when a big fat ball (LNP i.e. PEG) hits your cell surface.

This (see below) was changed in the updated version of the article (lolz):

*specific (viral, fungal and bacterial) stimuli. The response 
of innate immune cells to TLR4 and TLR7/8 ligands was 
lower after BNT162b2 vaccination, while fungi-induced 
cytokine responses were stronger. In conclusion, the 
mRNA BNT162b2 vaccine induces complex functional 
reprogramming of innate immune responses, which 
should be considered in the development and use of this 
new class of vaccines.

Mitogen = cell division
https://en.wikipedia.org/wiki/Mitogen
A mitogen is a small bioactive protein or peptide that induces a cell to begin cell division, or enhances the rate of division (mitosis). Mitogenesis is the induction (triggering) of mitosis, typically via a mitogen. The mechanism of action of a mitogen is that it triggers signal transduction pathways involving mitogen-activated protein kinase (MAPK), leading to mitosis.

Uncontrolled cell division =cancer (see the Tumor cell)

36 min KRAS -Mutant non-small cell lung cancer: From biology to therapy
https://www.researchgate.net/publication/326517018_KRAS_-Mutant_non-small_cell_lung_cancer_From_biology_to_therapy

37 min BNT162b2 vaccination enhances interferon-JAK-STAT-regulated antiviral programs in COVID-19 patients infected with the SARS-CoV-2 Beta variant
https://www.nature.com/articles/s43856-022-00083-x

Supplementary Data 3
Link: https://static-content.springer.com/esm/art%3A10.1038%2Fs43856-022-00083-x/MediaObjects/43856_2022_83_MOESM5_ESM.xlsx
Interferon up-regulated
He dug into the spreadsheet  RAS over-expressed

P53 tumor expresses up-regulated or down-regulated? More like dysregulated i.o.w out of balance.

In yeast and fungi, the Ras signalling casscade determines gene expression while attenuating growth as well as morphogenetic transformations in response to different environmental conditions.

48 min Regulation of mRNA Translation by Signaling Pathways
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536343/

modulating phosphorylation status = energy =fine tuned and malfunction leads to cancer (but just smack it with a blob on Synthetic lipid that encases mRNA -she’ll be right mate-lolz).
Don’t worry we thought of everything:

51 min Immune modulatory effects of oncogenic KRAS in cancer

https://www.nature.com/articles/s41467-020-19288-6

Some alterations induced by oncogenic KRAS mutations in cancer promote tumour cell proliferation (mitogenic effects), whereas other immune-modulatory effects allow the tumours to evade immune-mediated attack by creating an immunosuppressive microenvironment

55 min Increased PD-L1 surface expression on peripheral blood granulocytes and monocytes after vaccination with Sars-CoV2 Mrna or vector vaccine
https://pubmed.ncbi.nlm.nih.gov/36245120/

PD-L1= Programmed death-ligand 1. A protein that acts as a kind of “brake” to keep the body’s immune responses under control.

Up regulation PD-L1 lowers TCell responses to tumors

57 min Bombshell paper
Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536038/
Both the MRNA and the protein that it expresses can cross the nuclear membrane
therefore nuclear integration.

1:03 min SARS-CoV-2 mRNA vaccine is re-adenylated in vivo, enhancing antigen production and immune response
https://www.biorxiv.org/content/10.1101/2022.12.01.518149v2

Adenylation is an elegant biological process used to chemically activate carboxylate substrates by condensing them with ATP to liberate pyrophosphate.
https://en.wikipedia.org/wiki/Adenylylation

The poly-A tail is a long chain of adenine nucleotides that is added to a messenger RNA (mRNA) molecule during RNA processing to increase the stability of the molecule.
The poly-A tail makes the RNA molecule more stable and prevents its degradation. Additionally, the poly-A tail allows the mature messenger RNA molecule to be exported from the nucleus and translated into a protein by ribosomes in the cytoplasm.
https://www.nature.com/scitable/definition/poly-a-tail-276/

1:07 min MicroRNA video

Biogenesis of MiRNAs and mode of action

Understanding the pathway leading to the formation and function of microRNA
https://youtu.be/j-zTy6vOP3M

All the videos are on the substack

https://genervter.substack.com/p/der-weg-richtung-himmel-oder-holle

1:18 min natural RNa is proof read but the synthetic version is not proofread and can be frameshifted transcription errors misreading which means protein misfolding neurodegenerative disorders.

1:25 min Quantum microRNA Assessment of COVID-19 RNA Vaccine: Hidden Potency of BNT162b2 SASR-CoV-2 Spike RNA as MicroRNA Vaccine

https://crimsonpublishers.com/aics/fulltext/AICS.000552.php

Built into the genetic code of the spike protein are mimickry like microRNAs

There are inverse microRNAs that will cancel each other out (lolz)

1:30 min Inhibition of miR-21 Regulates Mutant KRAS Effector Pathways and Intercepts Pancreatic Ductal Adenocarcinoma Development
https://pubmed.ncbi.nlm.nih.gov/32409593/

What can happen if you over or under express….

An RNA hairpin is an essential secondary structure of RNA. It can guide RNA folding, determine interactions in a ribozyme, protect messenger RNA (mRNA) from degradation, serve as a recognition motif for RNA binding proteins or act as a substrate for enzymatic reactions.
Short hairpin RNAA short hairpin RNA or small hairpin RNA (shRNA/Hairpin Vector) is an artificial RNA molecule with a tight hairpin turn that can be used to silence target gene expression via RNA interference (RNAi)Expression of shRNA in cells is typically accomplished by delivery of plasmids or through viral or bacterial vectors. https://en.wikipedia.org/wiki/Short_hairpin_RNA

mIRN21 is one of the most frequently up-regulated miRNAs in solid tumors
https://en.wikipedia.org/wiki/MIRN21

1:34 min How do microRNAs regulate gene expression?
https://pubmed.ncbi.nlm.nih.gov/19021530/

1:56 min 

miRNAs (microRNAs) are short non-coding RNAs that regulate gene expression post-transcriptionally. They generally bind to the 3'-UTR (untranslated region) of their target mRNAs and repress protein production by destabilizing the mRNA and translational silencing. The exact mechanism of miRNA-mediated translational repression is yet to be fully determined, but recent data from our laboratory have shown that the stage of translation which is inhibited by miRNAs is dependent upon the promoter used for transcribing the target mRNA. This review focuses on understanding how miRNA repression is operating in light of these findings and the questions that still remain.

1:37 min  Circulating extracellular vesicle microRNAs associated with adverse reactions, proinflammatory cytokine, and antibody production after COVID-19 vaccination
https://www.nature.com/articles/s41541-022-00439-3

An in silico pipeline approach uncovers a potentially intricate network involving spike SARS-CoV-2 RNA, RNA vaccines, host RNA-binding proteins (RBPs), and host miRNAs at the cellular level https://pubmed.ncbi.nlm.nih.gov/36066672/

Our in silico analysis could aid in shedding light on the potential effects of exogenous RNA (i.e. viruses and vaccines), thereby improving our understanding of the cellular interactions between virus and host biomolecules. Finally, using the computational approach, it is possible to obtain a safety assessment of RNA-based vaccines as well as indications for use in specific clinical conditions.

miRNAs as a Potential Biomarker in the COVID-19 Infection and Complications Course, Severity, and Outcome
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047241/

1:45 min after 2nd shot of BNT162b2 oncogenic miR-21 is significantly upregulated

The microRNA’s detected in the plasma of pregnant women who had recieved three doses of the Moderna.

1:56 min Lifelong epigenetic changes

KRAS Hijacks the MicroRNA Regulatory Pathway in Cancer
https://pubmed.ncbi.nlm.nih.gov/36946612/

2:00 min miR-16 and miR-21 Expression in the Placenta Is Associated with Fetal Growth
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115987/

They knew:

2:03 min Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(18)30322-6

2:06 min Turbo cancer (stabilized miRna21)

Lost three years on the epigenetic clock

2:09 min Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination
https://pubmed.ncbi.nlm.nih.gov/35719387/

2:13 min miR29 dysregulated
Epigenetic Changes Mediated by MicroRNA miR29 Activate Cyclooxygenase 2 and Lambda-1 Interferon Production during Viral Infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255816/

Skewed fate and hematopoiesis of CD34+ HSPCs in umbilical cord blood amid the COVID-19 pandemic.
https://europepmc.org/article/pmc/pmc9650991

We detected upregulation of miR-29s and miR-142-3p during myeloid differentation in leukemia cell lines and CD34 hematopietic stem/progenitor cells

2:43 min Point of care vaccines – they will spin up a personalized vaccine for you at the pharmacy.

Conclusion

I praise you because I am fearfully and wonderfully made;
    your works are wonderful,
    I know that full well. (Ps 139:14)

Life is far more complex than they think. Fools rush in were angels fear to tread…but this is worse…much worse because it cannot all be put down to incompetence. They knew and they are experimenting on us.

Davey Crocko King of the wild frontier

Posted on

Davey Crocko King of the wild frontier

After the intro the stream commences (at about 12 min) with a tribute to Davey Marcello aka “Davey Croko” who recently passed away (if you just want the science skip to about 1:30).

He was a young man who struggled with addiction and the black dog and he was unvaccinated. The family did not release the circumstances around his death or publish an obituary.  Davey’s work in orphanages and child abuse and experimenting was in depth and somewhat groundbreaking. Davey streamed with Kevin and introduced him to the streaming scene.  Davey Crocko was a truth warrior who brutally took down and exposed con-men and grifters like Owen Benjamin.  For that reason I have called Davey “king of the wild frontier”, (the internet is the new wild west) as he was dogged at exposing the liars and he was a good researcher and citizen journalist.

The Ballad of Davy Crockett (2 min)

The funeral service is held today and Benjamin Owen is already dancing on the grave.  It really is hateful but we have no need of “hate speech laws” as Dr McCairn ripped shreds off him.  Not very edifying but the internet is the wild west and it has a way of self-cleansing and correcting itself. Let us hope that everyone notes Owen’s despicable behavior and shuns him. We are losing a lot of good people, that is the second one in just over a week. All his research and video material is being archived on WTYL (the raccoon server) so that it will not be lost.

RIP Davey.  RIP Mike.

Brain Puss and PD

The stream also examines a very important paper on Parkinson Disease (PD).  Early onset PD in younger people has increased significantly and neurological disease in general has increased including children getting brain abscess filled with puss. I wonder what could be causing that?

CDC is Investigating an Alarming Cluster of Mysterious Brain Infections in Children in Nevada (2 min)

The scientific papers begin roughly at 1:31 with a brief examination of The original strain of SARS-CoV-2, the Delta variant, and the Omicron variant infect microglia efficiently, in contrast to their inability to infect neurons: Analysis using 2D and 3D cultures followed by…

Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol   …

…but this one is extensively treated and is very good (recommended):

Abstract Parkinson's disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer's disease, globally. Dopaminergic neuron degeneration in substantia nigra pars compacta and aggregation of misfolded alpha-synuclein are the PD hallmarks, accompanied by motor and non-motor symptoms. Several viruses have been linked to the appearance of a post-infection parkinsonian phenotype. Coronavirus disease 2019 (COVID-19), caused by emerging severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, has evolved from a novel pneumonia to a multifaceted syndrome with multiple clinical manifestations, among which neurological sequalae appear insidious and potentially long-lasting. Exosomes are extracellular nanovesicles bearing a complex cargo of active biomolecules and playing crucial roles in intercellular communication under pathophysiological conditions. Exosomes constitute a reliable route for misfolded protein transmission, contributing to PD pathogenesis and diagnosis. Herein, we summarize recent evidence suggesting that SARS-CoV-2 infection shares numerous clinical manifestations and inflammatory and molecular pathways with PD. We carry on hypothesizing that these similarities may be reflected in exosomal cargo modulated by the virus in correlation with disease severity. Travelling from the periphery to the brain, SARS-CoV-2-related exosomal cargo contains SARS-CoV-2 RNA, viral proteins, inflammatory mediators, and modified host proteins that could operate as promoters of neurodegenerative and neuroinflammatory cascades, potentially leading to a future parkinsonism and PD development.

In the context of Dr McCairn’s discussion of this important paper I have added the last two parts of the Merogenomics series on shedding by Dr. Raszek (the other two parts can be found here: https://www.biblaridion.info/blog/notification-shedding/)

Shedding Investigation Part 4: exosomes in COVID-19 (update 86)-30 min

Did you know that these tiny vesicles (exosomes) carry the elusive spike protein, which has been found to be a key player in the progression of COVID-19 disease?

Shedding Investigation Part 5: exosomes in COVID-19 (update 88)- 27 min

We explore groundbreaking information that shows COVID-19 patients can produce exosomes with spike proteins that can trigger an immune system response. But the big question remains: Can these exosomes be breathed out by infected patients? Don't miss out on the exciting conclusion of this series where we provide our final analysis and conclusion on this intriguing topic.

Now the stream from Dr Kevin McCairn

Shaming Owen Benjamin, Irish Information Disorder, SARS-Parkinsonism (exosome hypothesis)

 Conclusion

Dr. Raszek concludes the following:

1. Exosomes can be breathed out
2. Exosomes can carry spike protein
3. Exosomes can stimulate the immune system (like a virus does)
4. Exosomes can be shed (a reasonable assumption more study needed)

I pointed this out two years ago and lost an account when I said this.  Dr Kevin McCairn warned about the neurological and incapacitating aspect of this bioweapon …because that is what it is…a bioweapon.  Think of it as  aerosolized HIV.   This is pure evil. It has multiple pathways of attack and  once in the system it can kill the gut bacteria and travel up the vagus nerve to the brain.  The vagus nerve is responsible for the regulation of internal organ functions, such as digestion, heart rate, and respiratory rate, as well as vasomotor activity, and certain reflex actions, such as coughing, sneezing, swallowing, and vomiting. Some people suffer constant diarrhea.  Others suffer T-cell exhaustion (from constant infections) and reduction in white blood cells. Now we know that the production process for  the vaccines contaminated them with plasmid DNA which included SV40 promoter (cancer trigger).  So there is “free DNA” in the vaccine allowing the possibility to “write” the Spike Protein into nucleic DNA which may explain why it can still be found in the blood a year later.  The fact is that different people will respond differently, because there is genetic diversity.  Some people will hardly get sick.  Others will experience rapid aging and the diseases of old age.  Others will be taken out straight away with clots or heart attacks.  I am telling you now (believe me) that they are hiding the death numbers.  The fact is that a lot of people will die prematurely from different diseases and this makes it difficult to join the dots.  It is a long term agent with multiple attack vectors. A very clever and deadly weapon.   And that is not all because another long term consequence is infertility.  This is a slow motion genocide.

As Dr Kevin McCairn pointed out, people like Kaufman who pushed the “no virus theory” (and others who did the same) focused on exosomes as a “natural means of the body detoxing”.  They were controlled opposition brought into the picture to muddy the waters surrounding exosomes.   They wanted anyone looking into exosomes labelled as a crank.   The truth has a way of always coming out and exposing the darkness.

Charles Rixey and Christie Grace

Posted on

Charles Rixey and Christie Grace

Listening to this in the background.  Rixey traveled to see JFK Jr who gave a speech regarding Presidential candidacy at a Hotel were someone pulled the fire alarm there was a mess up with his ticket (silver not gold) so he did not get to see him at the reception but Bret Weinstein put in a good word for Rixey. Remember Rixey used to work for JFK before he got back stabbed by JC and Rixey has teamed up with Andrew Huff who used to work with Daszak  as a former employee of the EcoHealth Alliance before he became a whistleblower. I always thought him a bit suspect but he keeps coming up with the goods.  Now for something funny….apparently Mel Gibson wants to make a movie about Huff and offered Charles Rixey a part to play himself and maybe other members of the Raccoon resistance.  I am booking in for a haircut and getting an agent right now (lolz).

Still got to listen to the rest….may add more comments later (so busy….).

So, completed listening to  the stream and Grace did not appear, instead we had Nick who is very knowledgeable in the field. They discussed Charles’ document:

Interesting comment by Nick on cancer prevention and treatment where he promotes tea made from organic Pomegranate peel, Orange peel, Dandelion root and Lion’s Mane. We will have a look at some of these treatments in a health article.

 

Streaming With Charles Rixey & Christie Grace: Latest Bio-Warfare Updates (4:25)

Slaughtered & Skewered Mutton

Posted on

Slaughtered & Skewered Mutton

Very important. Show no quarter.  These people enable murder.  Your weapon is the truth.

Man he is on fire and angry

Watching this now late at night live but I need to go to bed soon.  Here we have Dr Kevin McCairn giving the troops a pep talk to fight and keep fighting.  He is taking on the Mutton Crew and citing the articles to take on the Kapos.   A Kapo is a prisoner in a concentration camp who sells out and becomes a guard. He rats out everyone to save his own skin.

The Mutton Crew – they brought in the sheep herding virologist from Yorkshire (Swaledale mutton) backed up by a crew.  They are military intelligence or paid by them.  Known as Brigade 77.

These are the papers that you need to refute their garbage.  They can’t answer them.  They run and hide or launch ad hominem attacks.  They are liars and gaslighters paid to spout propaganda and gaslight.  They are scum.  People have died because of what they are still doing.    You are at war  and the war is against you and your loved ones (click to expand the tweet for all the links to the articles)

Slaughtered & Skewered Mutton (A Treatise On Eviscerating Kapos (2:34)