Virus evolution and LNP
The Explosion of Cancer and Latent Disease: The Lipid Nanoparticle Platform Is Asking for Trouble (5 min)
Virus evolution by antibodies + BA 2 Omicron – COVID-19 vaccines update 40 (17 min)
How does the virus evolve inside an infected person – we commence this story with a new demonstration in a vaccinated patient, and relapse to a well-documented history in COVID-19 patients, and how antibodies can be contributing to such viral evolution. This also leads us to a hypothesis as to why evolving variants might show up in wastewater prior to taking over a population. We conclude with how the BA2 variant of the Omicron is different from the BA1 variant, demonstrating continuous uninterrupted evolution of the virus.
Described content: Vaccine patient variants: https://www.sciencedirect.com/science… Variants database: https://cov-lineages.org/lineage_list… Innunocompromised host: https://www.nejm.org/doi/10.1056/NEJM… Cancer host: https://linkinghub.elsevier.com/retri… HIV host: https://www.medrxiv.org/content/10.11… Prolonged infection variants: https://academic.oup.com/ve/article/7… Evolution speed: https://www.clinicalmicrobiologyandin… Immune escape co-evolution: https://www.science.org/doi/10.1126/s… Convalescent plasma host: https://www.nature.com/articles/s4158… GIT variant evolution: https://genomemedicine.biomedcentral…. GIT viral load: https://www.gastrojournal.org/article… Viral load impact: https://academic.oup.com/ve/article/7… BA2 Omicron: https://arxiv.org/abs/2202.05031